The sixth DREAM consortium paper is out in Nature Methods. The consortium is a community effort for systematically comparing expression-based network inference methods. A major finding of the paper is that combining different methods has the best performance. This year’s competition analyzed datasets from a simulated network, the E. coli regulatory network, and the yeast S. cerevisiae regulatory network. Methods do well in for simulated and E. coli, but the performance is poor for yeast.