Daily Archives: June 19, 2017


Visualization and analysis of single-cell RNA-seq data by kernel-based similarity learning

Our next meeting will be at 3:00 on June 23th, in room 4160 of the Discovery building. Our Selected paper is Visualization and analysis of single-cell RNA-seq data by kernel-based similarity learning.
The abstract is as follows.

We present single-cell interpretation via multikernel learning (SIMLR), an analytic framework and software which learns a similarity measure from single-cell RNA-seq data in order to perform dimension reduction, clustering and visualization. On seven published data sets, we benchmark SIMLR against state-of-the-art methods. We show that SIMLR is scalable and greatly enhances clustering performance while improving the visualization and interpretability of single-cell sequencing data.

We welcome all who can join us for this discussion. Feel free to begin that discussion in the comments section below.